Monoclonal antibodies 3.5 / 5 based on 3 ratings ? BiologyMicrobes and diseaseGCSEAQA Created by: ZayedZakerCreated on: 03-09-16 17:55 What are antibodies produced by? B-lymphocytes 1 of 12 How are monoclonal antibodies produced? From lots of clones of one single white blood cell 2 of 12 What does it mean if the antibodies are monoclonal? They are all identical and only target a specific protein antigen 3 of 12 How can a Hybridoma cell be created? By fusing a mouse B- lymphocyte with a tumour cell 4 of 12 Why are monoclonal antibodies really useful? They can bind to target a specific cell or chemical in the body because of the antigen on it's surface 5 of 12 What happens to the hybridoma cell once created? Can be cloned to produce many identical antibodies 6 of 12 What can monoclonal antibodies be used to diagnosis? Weather a woman is pregnant/not 7 of 12 What are tumour markers? Cancer cells have different antigens attached to their cell membranes called this 8 of 12 What is attached to the monoclonal antibodies to treat cancer? A anti-cancer drug or radioactive substance can be attached to stop the cancer cells growing or dividing 9 of 12 What is the advantage of using monoclonal antibodies to treat cancer? They only target cancer cells not normal cells 10 of 12 What is the disadvantage of using monoclonal antibodies? They have more side effects than expected 11 of 12 What can monoclonal antibodies be used to? Locate a specific molecule on cell/tissue by attaching it to a fluorescent dye to detect them 12 of 12
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