Vibrio cholerae is ingested. It releases a toxin which binds to a receptor on the gut wall. It is brought into the epithelial cell via endocytosis. Leakage of CL- ions and HCO3- ions into gut lumen, causing water to be drawn into the lumen.
20 of 31
Name 2 treatments for cholera
Rehydration treatment via IV drip, antibiotics
21 of 31
Where are proton pumps located?
In the PARIETAL CELLS of the stomach lining/epithelium
22 of 31
What causes the high acidity of the stomach lumen?
Active exchange of K+ with H+ at the Proton pump
23 of 31
What is the infective cause of stomach ulcers?
Helicobacter Pylori bacterium
24 of 31
Name 3 treatments for Stomach ulcers
Proton Pump inhibitors, Antibiotics, Bismuth
25 of 31
What can cause stomach ulcers?
high HCL, low mucus levels
26 of 31
What secretes hormones?
endocrine (ductless) glands
27 of 31
What secretes enzymes?
exocrine (through a duct) glands
28 of 31
What is nervous regulation of gastric juice?
thought, smell, sight of food causes secretion of HCL from parietal cells of stomach wall
29 of 31
What is the function of the Vagus nerve?
to signal for the production of the hormone Gastrin .
30 of 31
What is the function of Gastrin?
to stimulate the production of pepsinogen, which activates to become pepsin
31 of 31
Other cards in this set
Card 2
Front
What can cause high levels of LDL?
Back
Bad diet, Smoking, Genetic factors - familial Hypercholesterolaemia
Card 3
Front
Name 2 possible medical treatments for high LDL:HDL or CHD
Back
Card 4
Front
List 3 PHYSIOLOGICAL (not cellular) functions of cholesterol
Comments
No comments have yet been made